Ion-exchange complex of famotidine: sustained release and taste masking approach of stable liquid dosage form
نویسندگان
چکیده
منابع مشابه
Ion-exchange complex of famotidine: sustained release and taste masking approach of stable liquid dosage form.
A stable controlled release resinate-complex for the highly bitter taste famotidine (FAM) was developed to allow once-daily administration and improve patient compliance especially in pediatric and geriatric medicine. The drug-resinate complexes were prepared in different drug to resin (Amberlite IRP-69) ratios by weight (1:1, 1:2, 1:3, 1:4, 1:5 and 1:6). The optimized drug-resinate complex res...
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An attempt was made to sustain the release of metformin HCl as well as to mask the bitter taste by complexation technique using strong cation-exchange resins, indion 244 and indion 264. The drug loading onto ion-exchange resin was optimized for mixing time, activation, effect of pH, mode of mixing, ratio of drug:resin and temperature. The resinate was evaluated for micromeritic properties, tast...
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ژورنال
عنوان ژورنال: Drug Discoveries & Therapeutics
سال: 2014
ISSN: 1881-7831,1881-784X
DOI: 10.5582/ddt.2014.01043